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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP3
All Species:
25.76
Human Site:
Y37
Identified Species:
47.22
UniProt:
P42574
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42574
NP_004337.2
277
31608
Y37
G
I
S
L
D
N
S
Y
K
M
D
Y
P
E
M
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
Y37
G
I
S
L
D
N
S
Y
K
M
D
Y
P
E
M
Rhesus Macaque
Macaca mulatta
XP_001083044
277
31383
Y37
G
I
S
L
E
N
S
Y
K
M
D
Y
P
E
M
Dog
Lupus familis
XP_544026
359
40231
A109
S
G
R
S
I
K
T
A
Q
D
Q
V
P
T
Y
Cat
Felis silvestris
Mouse
Mus musculus
P70677
277
31456
Y37
G
I
Y
L
D
S
S
Y
K
M
D
Y
P
E
M
Rat
Rattus norvegicus
P55213
277
31473
Y37
G
I
Y
L
D
S
S
Y
K
M
D
Y
P
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517122
293
32326
Y53
S
A
S
L
D
D
R
Y
R
M
D
Y
P
N
M
Chicken
Gallus gallus
Q98943
424
47941
F56
I
Q
A
K
S
G
S
F
S
Q
N
V
E
F
L
Frog
Xenopus laevis
P55866
282
32106
H44
E
R
K
T
K
F
A
H
L
Q
N
Y
R
T
N
Zebra Danio
Brachydanio rerio
NP_571952
282
31503
Y40
P
Q
S
H
A
F
R
Y
S
L
N
Y
P
N
I
Tiger Blowfish
Takifugu rubipres
NP_001027871
280
30520
Y43
P
A
A
Y
S
F
R
Y
S
L
D
F
P
N
M
Fruit Fly
Dros. melanogaster
O01382
339
37345
P66
L
A
N
G
Y
S
S
P
S
S
S
Y
R
K
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
T79
F
Y
D
A
L
R
S
T
G
H
E
G
L
A
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.6
43.4
N.A.
86.6
89.1
N.A.
65.1
22.1
54.6
55.6
56.4
35
N.A.
20.6
N.A.
Protein Similarity:
100
100
98.5
57.9
N.A.
93.8
93.8
N.A.
76.1
40.3
69.1
69.5
71
48.9
N.A.
36.1
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
60
6.6
6.6
26.6
26.6
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
73.3
33.3
26.6
46.6
46.6
33.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
16
8
8
0
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
39
8
0
0
0
8
54
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
8
0
8
39
8
% E
% Phe:
8
0
0
0
0
24
0
8
0
0
0
8
0
8
0
% F
% Gly:
39
8
0
8
0
8
0
0
8
0
0
8
0
0
0
% G
% His:
0
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
8
39
0
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
8
8
8
0
0
39
0
0
0
0
8
0
% K
% Leu:
8
0
0
47
8
0
0
0
8
16
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
47
0
0
0
0
54
% M
% Asn:
0
0
8
0
0
24
0
0
0
0
24
0
0
24
16
% N
% Pro:
16
0
0
0
0
0
0
8
0
0
0
0
70
0
0
% P
% Gln:
0
16
0
0
0
0
0
0
8
16
8
0
0
0
0
% Q
% Arg:
0
8
8
0
0
8
24
0
8
0
0
0
16
0
0
% R
% Ser:
16
0
39
8
16
24
62
0
31
8
8
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
8
8
0
0
0
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
16
8
8
0
0
62
0
0
0
70
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _